Sentence examples for multiple pathological insults from inspiring English sources

In liver, it was found that autophagy plays important roles in cytoprotection against multiple pathological insults, including liver steatosis, liver injury, dyslipidemia in alcoholic, and non-alcoholic fatty liver conditions [ 17– 20].

Dysregulation of cell metabolism occurs under multiple pathological conditions.

Cardiac fibroblasts help maintain the normal architecture of the healthy heart and are responsible for scar formation and the healing response to pathological insults.

We conclude that USP20 regulates β1AR signaling in vitro and in vivo Additionally, β1AR-induced USP20 phosphorylation may serve as a feed-forward mechanism to stabilize β1AR expression and signaling during pathological insults to the myocardium.

Our study suggests that TGFβ contributes to multiple pathological processes responsible for oral mucositis development.

Thus, in response to external pathological insults, hemichannels can alter cell physiology directly [27].

Hmox1 catalyzes the rate-limiting step in heme degradation and is involved in protecting cells against various pathological insults including ischemic injuries and peroxide toxicity [93], [94].

The boundary between normal physiological changes and pathological insults is therefore inevitably indistinct.

We asked why miR-874 is upregulated in response to the pathological insults.

ZO-1 is important for maintaining the integrity of intestinal mucosal TJs during pathological insults [ 21].

Oxidative stress is considered one of the potential pathological insults given by maternal hypercholesterolemia on placenta and fetuses.