The interferon-inducible transmembrane protein-3 (isITM3) is a protein that restricts multiple pathogenic viruses such as influenza virus.
The mechanisms of neuronal degeneration characterizing PD have been studied extensively and include a complex interplay among multiple pathogenic processes including oxidative stress, protein aggregation, excitotoxicity and impaired axonal transport [ 7].
Using bacterial toxins, we describe a new approach for discovering broad-spectrum therapies capable of inhibiting host proteins that mediate multiple pathogenic pathways.
Using B-lymphoblastoid cells derived from the HapMap Project cohort of persons of African, European, and Asian ancestry we identified host caspases as hub proteins that mediate the lethality of multiple pathogenic agents.
Mechanisms include alteration of the microbial protein physiology destroying structural pathogenic proteins and metabolic enzymes.
Guo, J. L. & Lee, V. M. Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases.
Asthma is a complex disease involving multiple pathogenic features including inflammation, mucus secretion, remodeling and bronchoconstriction.
Intracellular furin processes its multiple normal cellular targets in the Golgi and secretory vesicle compartments while cell-surface furin appears to be essential only for the processing of certain pathogenic proteins and, importantly, anthrax.
Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial "pan-genome".
This technique is potentially useful for high throughput screening of multiple pathogenic bacteria in different samples.
