Sentence examples for multiple pathogenic pathways from inspiring English sources

These alterations in gene expression span multiple pathogenic pathways, including amyloid β peptide (Aβ) processing, tau hyperphosphorylation, and inflammation, among others.

Instead, our understanding of RA as a clinical phenotype is devolving into multiple pathogenic pathways.

However, all euphoria should not let forget that JAK inhibitors inhibit multiple pathogenic pathways simultaneously.

Second, JAK inhibitors inhibit multiple pathogenic pathways simultaneously, including both type I and type II IFN receptor pathways, both of which appear to be active in AA (Xing et al., 2014, Freyschmidt Paul et al., 2006, Ghoreishi et al., 2010).

Moreover, in addition to individual risk factors, conference participants recognized a need for further understanding of how risk factors interact as they contribute to the multiple pathogenic pathways that may ultimately result in PD.

The clinical definition of the three main subsets of patients emerges as a crucial point: our data are in line with the conclusion of a recent reappraisal of serum biomarkers in "high-risk" pregnancies: "multiple pathogenic pathways lead to the disease recognized clinically as preeclampsia" [ 27].

PD is a complex disorder, and multiple different pathogenic pathways and mechanisms can ultimately lead to PD.

Based on existing evidence, we are confident of the following: PD is a complex disorder, and multiple different pathogenic pathways and mechanisms can ultimately lead to PD.

27– 29 It may be argued that in future the further increase in the number of susceptibility genes identified for metabolic disorders will lead to considerable improvement of the predictive power of genotypic biomarkers in polymorphism and gene combinations of increasing complexity, affecting multiple target tissues and pathogenic pathways.

Together, this evidence suggest that OXR1 functions upstream of multiple neuroinflammatory pathways during ALS pathogenesis, and that addressing multiple pathogenic mechanisms may be required to improve survival due to compensatory pathways.

While not a rheumatic disease, studies on pathogenic pathways in the autoimmune disease multiple sclerosis have been highly informative in deciphering immune abnormalities that lead to immune-driven tissue damage.