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Considering the multiple pathogenic mechanisms, multi-mechanism-targeted therapy may have better effect than monotherapy.
Multiple pathogenic mechanisms contribute towards the development of anaemia in critically ill patients.
Applying different medications to intervene at every key point of the multiple pathogenic mechanisms may bring us closer to a better outcome.
Due to the multiple pathogenic mechanisms causing manifestations of CNS lupus, there is no single confirmatory diagnostic test available.
In multiple trials, topical combination therapies are more effective than monotherapy as they are capable of targeting multiple pathogenic mechanisms.
Aspirin can modulate multiple pathogenic mechanisms implicated in the development of multiple organ dysfunction in sepsis and ARDS.
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These findings suggest that the use of small molecule p75NTR ligands may be a therapeutically feasible approach to AD capable of simultaneously targeting multiple underlying pathogenic mechanisms.
Together, these results indicate that the progression of neuropathy in C22 mice is underlined by multiple ongoing pathogenic mechanisms, including intrinsic subcellular events within Schwann cells and extrinsic soluble factor-mediated processes, such as macrophage infiltration.
The miRNAs involved in cardiovascular disease in diabetes are summarized in Figure 3 B. Diabetic retinopathy (DR), one of the leading causes of blindness in developed countries, is a microvascular complication of diabetes with multiple underlying pathogenic mechanisms.
Indeed, specific neuroanatomical and morphological properties of select neuronal populations combined with alterations in multiple synergistic pathogenic mechanisms likely explain the variable clinical presentation of neurodegenerative diseases associated with Lewy pathology.
The unexpected magnitude of this overlap presents the unique opportunity to dissect the pathogenic mechanisms underlying multiple disease states in the expectation that this may lead to both more sensitive diagnostics and novel therapies.
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various pathogenic mechanisms
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multiple resistance mechanisms
multiple causative mechanisms
multiple disease mechanisms
multiple pathogenic isolates
multiple pathogenic processes
multiple combined mechanisms
multiple pathogenic events
multiple pathogenic influences
multiple pathogenic proteins
multiple pathogenic categories
multiple pathogenic pathways
multiple pathogenic mutations
multiple pathogenic targets
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