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Comparative genomic analysis showed that multiple paralogues of acp and fabF are not unusual.
Insects generally have two Snmp genes (Snmp1 and Snmp2), but some species have multiple paralogues of Snmp1[ 57].
Within bacteria, there are multiple paralogues of the EF2 family, the most distinctive being TypA, LepA, Tet, RF3, EFGII, gcEFG, spdEFG1 and spdEFG2.
The multiple paralogues of SigB, a group 2 sigma factor, have been classified as SigB (All7615), SigB2 (Alr3800), SigB3 (All7608), and SigB4 (All7179).
Most of the genes that were present existed as a single copy, but multiple paralogues of acyl carrier protein (acp, 3 copies) and β-ketoacyl-ACP synthase (fabB and fabF, 7 copies) were identified in the lipid gene clusters.
Overall, a conserved core of the reconstructed Zur regulons includes one or multiple paralogues of the zinc ABC-type transporter ZnuACB and a putative P-loop GTPase of the COG0523 family [ 34], orthologues of the B. subtilis YciC protein [ 35].
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In support of this, expansion of Group 1 receptor chains within teleosts that has produced multiple paralogues for the PRLR/GHR subgroup.
While mammalian genomes contain multiple paralogues for most groups, invertebrates typically have fewer Sox genes.
All possible solutions are returned, allowing coevolution between specific or multiple paralogues to be discovered.
The variation observed in multiple CCMP421 strain synonyms appears to be caused by the presence of multiple paralogues, which was not observed in MAC-579 (clade B).
The one exception to this were clonal DNA barcodes of CCMP421, where the average distance between all clones plus the direct sequence was 1.3%, a value expected for an average intra-species comparison and likely to be due to the presence of multiple paralogues.
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