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As a result, a loss of cas genes requires multiple parallel events of loss whereas the cas acquisition only requires one transfer.
This implies multiple parallel events of hsd locus insertion into orfX.
For example, the question of how many parallel changes are required to be recognized as an instance of concerted change is naturally dealt with in our model: the statistical signature of concerted or regular change is that the multiple parallel events are more probable if treated as a single coordinated change than as a collection of independent changes (Box 1).
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These mutations occur significantly more frequently together than alone in the complete Yg6 dataset, suggesting these mutations are shared by descent from a new source gene, rather than by multiple parallel mutation events.
Multiple parallel evolutionary events may be possible on the Heliconius genetic background, but given that DNA introgression occurs, it does not seem unlikely that the occasional hybridization and backcrossing we document has led to transfer of alleles suitable for different mimetic environments.
Again, it is difficult to say whether this clustering is due to multiple, parallel expansion events within a lineage, the current mainstream interpretation, because of the potentially confounding effect of codon usage variation across species [ 81] that may hinder phylogenetic reconstruction.
Given the resources being ploughed into research on development (DFID alone spends about £350m a year), surely it would be a worthwhile investment, if it hasn't already been done, to sponsor a research programme that runs multiple parallel experiments with different event formats, and compares the results in terms of participant feedback, how much people retain a month after the event etc?
This is true for single and multiple event type experiments, which allow either parallel events (overlapping events design) or designs in which only one event occurs at a time (nonoverlapping events design).
The 'unitary event' analysis method was designed to analyze multiple parallel spike trains for correlated activity.
As a consequence, the dish contained multiple parallel inoculation strips.
Two cases of parallel pathways, (1) musical artifacts and (2) large-scale interactive artifacts, are presented in this paper to demonstrate the multiple, parallel pathways that Makers take to making their artifacts and the contextual events and activities that are critical to the direction of these pathways.
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