This approach was successful in models glioma amongst multiple other tumour types (Kim et al, 2008).
By integrating multiple other data types, we narrowed this further to 13,211 representative transcripts.
More than 80% of other OH-only users in this study were exposed to sulfonylureas only, while 12% received multiple other OH types.
Tie2 is expressed predominantly by ECs, although some subsets of macrophages and multiple other cell types express Tie2 at low levels [ 69, 70].
Similar findings have been described in multiple other cell types treated with various pro-oxidants such as cisplatin [ 38] and thymoquinone [ 39].
PTK6, a member of a distinct family of non-receptor tyrosine kinases distantly related to Src kinases, is expressed in breast cancers and multiple other cancer types [ 3– 7].
In full accordance with the role of this protein in multiple other cell types, telomerase is required to maintain the replicative potential of pancreatic beta-cells.
Although FGFR activating mutations are found in multiple other cancer types, including FGFR2 in endometrial cancer [ 54] and FGFR3 in bladder cancer [ 55], there is no evidence for common mutational activation of the FGFRs in breast cancer.
In contrast, we found no evidence for methylation of P3H2 in analysis of cell lines from multiple other tumour types, including ovarian and renal adenocarcinomas, squamous carcinomas of the vulva and head and neck, malignant melanoma and glioma.
PIK3CA is one of the most commonly mutated oncogenes in human cancers, occurring at high prevalence in tumors of the colon, breast, ovary, stomach and liver, and at lower prevalence in multiple other cancer types.
