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Initially, the transcription factors OCT4, SOX2, KLF4, and cMYC or OCT4, SOX2, NANOG, and Lin2 were identified as crucial reprogramming genes, but multiple other combinations of fewer factors, in combination with miRNA or small molecules have also been described.
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In both diatoms and cryptophytes, dual or multiple targeting to other combinations of organelles (e.g., mitochondrion and cytosol, PPC and plastid) may still await discovery and would further our understanding of organelle targeting in these highly compartmentalized eukaryotes.
While it is still possible that this observation reflects changes in a combination of multiple other behavioral variables, none of the possible combinations of the behavioral measures was able to explain the observed accuracy difference between trained and untrained sequences.
It is common in wavelet image analysis to use multiple algorithms, iterative algorithms and other combinations of image processing techniques.
Our work provided broader application of RSM for the simultaneous detection of other combinations of multiple pathogens.
We next made crosses between ap2c1/ap2c2 with ap2c4/ap2c3 double mutants to obtain other combinations of multiple mutants.
Additionally, this instrument remains too long to be efficiently completed in combination with multiple other instruments within extensive longitudinal or idiographic studies.
The effective antibiotics may be expensive and may need to be given for a prolonged duration, often in combination with multiple other agents.
Given that the PR acts in combination with multiple other transcription factors to affect transcription, it is possible that variability of the tissue-specific expression of the components of this multiprotein complex may result in different PRA and PRB activities in the same cell.
In contrast, in vivo, a high biotin intake in combination with a low intake of multiple other nutrients has been associated with increased genomic stability [ 53].
Although some of the other combinations gave large changes, none were statistically significant after a Bonferroni correction for multiple comparisons was applied (see Supplementary Table S2).
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CEO of Professional Science Editing for Scientists @ prosciediting.com