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Yet, to what extent aquaculture escapees become established by means of high propagule pressure and multiple origins is not clear.
The possibility of multiple origins is difficult to determine since only two susceptible haplotypes have been retained by European and North American populations.
Lastly, splitting asexual taxa into single vs. multiple origins is not necessarily a good proxy for evaluating clonal recruitment rates because comparisons of clonal recruitment rates among unrelated asexual taxa are complicated (see Discussion in [ 13]).
27, 28 Determining whether all infections had a single origin (outbreak) or multiple origins is crucial for designing proper containment strategies, and DNA analysis can help in this task.
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DNA replication initiates from a single origin in bacteria, whereas multiple origins are utilized in eukaryotes [ 3].
In any case, alternative hypotheses, based on multiple origins, are technically possible but clearly implausible given the available data.
When a life habit has multiple origins, are these lineages the result of convergent evolution or parallel evolution?
When multiple origins are present in the cell, the DnaA molecules "ejected" from one origin after initiation of replication are used for the initiation at other origins.
The reduction of viremia and viral shedding is a highly desirable outcome of vaccination since this could prevent BVDV transmission in operations such as feedlots and stocker units where high numbers of cattle from multiple origins are commingled.
Haloarchaeal genomes are normally composed of multiple replicons (chromosome, minichromosome, and plasmids) with multiple Orc/Cdc6 homologs (usually more than 10 homologs) [ 19- 30], indicating that the occurrence of multiple replication origins is widespread in haloarchaea.
Our comparison analyses demonstrated that the dynamics of multiple replication origins is associated with the evolution of multireplicon genome architecture, which indicates that genome evolution forces origin dynamics in variable regions and that maintenance of the conservative replication origins may be promoted by their effects on surrounding genomic environments.
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