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They usually suffer from multiple oral diseases, and obstacles to their use of dental care services are numerous.
As consequence, middle-aged and elderly individuals usually suffer from multiple oral diseases, and obstacles to their use of dental care services are numerous [ 7].
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To treat their diseases, they often use multiple oral drugs.
Glycaemic goals are not achieved in most patients with type II diabetes mellitus (T2DM), especially in those with long disease duration and taking multiple oral antidiabetic drugs (OAD).
After the macaques received multiple oral doses, clinical signs of a spongiform disease had not developed by 6.5 (2 of 3 macaques) to 8.8 years (1 of 3 macaques) postinoculation although they received an LD100 on day 1 (Table 1).
4 Due to the complexity of the disease, many patients with T2DM require multiple oral anti-hyperglycemic agents (AHAs) and even insulin therapy to maintain adequate blood glucose control.
This is because one study of the medium dose versus placebo allowed the inclusion of patients receiving multiple oral drugs with or without insulin, which typically reflects advanced disease stages.
Such observations help us to understand why type 2 diabetes, a relentless progressive disease, requires advances from monotherapy with oral antidiabetic agents to combination therapy using multiple oral agents and finally insulin replacement without undue delay (34).
Oral diseases.
Indeed, DCs of the oral mucosa were demonstrated to be directly involved in various oral diseases.
Richards, D. Oral diseases affect some 3.9 billion people.
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