Sentence examples for multiple oncogenes including from inspiring English sources

Chromosome 8 has previously been implicated in prostate cancer progression, containing multiple oncogenes, including Myc (El Gammal et al, 2010).

miR-15a and miR-16-1 function by targeting multiple oncogenes, including BCL2, MCL1, CCND1, and WNT3A [ 33, 47].

The let-7 family of miRNAs plays an important role in tumorigenesis by regulating the expression of multiple oncogenes, including KRAS [ 4].

miR-15a, along with miR-16, is commonly deleted in human chronic lymphocytic leukemia [ 32] and known to target multiple oncogenes, including BCL2, MCL1, CCND1, and WNT3A [ 33].

In PCa oncogenesis, the miR-15a/16-1 cluster acts as a tumour suppressor by targeting multiple oncogenes, including BCL2, CCND1, and WINT3A (Bonci et al, 2008).

Cheng et al. [70] further found that ZNF382 inhibited NF-κB and AP-1 signaling and down-regulated the expression of multiple oncogenes, including MYC, MITF, HMGA2, CDK6, STAT3, STAT5B, ID1, and IKBKE, most likely through heterochromatin silencing.

Hsp90 is a molecular chaperone responsible for the folding and stability of multiple client proteins, many of which are oncogenes, including Akt, c-Raf, and Her-2 [ 2].

The increased expression of COX-2 in tumourigenesis is secondary to multiple activations and as a response to growth factors and oncogenes, including those in the EGFR/HER2/RAS/MAP kinase pathway.

For example, cellular senescence can be triggered by overexpression of some oncogenes, including activated RAS.

Additionally, this process induces the expression of oncogenes, including ID1.

The focal alteration of 3q27.1 spans various proto-oncogenes including ABCC5, ALG3, EIF4G1 and EPHB3.