Sentence examples for multiple oligonucleotide probes from inspiring English sources

Exact(6)

In the microarray data, genes are often represented by multiple oligonucleotide probes.

In the FISH protocol, multiple fluorescence reporters were heavily labeled on a single oligonucleotide and multiple oligonucleotide probes were hybridized to a mRNA target to ensure detection sensitivity.

For example Affymetrix is a single-channel platform, where multiple oligonucleotide probes (probeset) of 25 bases are used to measure the concentration of a mRNA transcript.

The procedure is of general applicability as a test for specificity and discriminatory power of microarray-based diagnostic procedures using multiple oligonucleotide probes.

ISHH detection sensitivity can also be enhanced by using multiple oligonucleotide probes to different regions of the designated mRNA, or by a number of amplification methods such as TSA (see Section 4.3 above).

After two screens (see Supplemental methods in Additional file 3 and Figure S1 in Additional file 4), we obtained a molecular profile of Her2+/TN with 1,304 genes (1,349 oligonucleotide probes; some genes were represented by multiple oligonucleotide probes in the Illumina BeadChip.

Similar(54)

Another interesting feature of the transcriptomic data is that by virtue of multiple oligonucleotide probe sets representing some genes on the array chip, a number of GPCR splice variants appear to be present in the PVN and SON.

GeneChip® arrays comprise multiple 25-mer oligonucleotide probes per gene and retain certain advantages over direct sequencing.

The Affymetrix GeneChip® platform (Affymetrix, Santa Clara, CA, USA) is a widely used microarray technology in which each gene on the microarray is represented by multiple 25-mer oligonucleotide probes.

Finally, all databases mentioned have no options for analyses based on GCOS comparison statistics, a particular algorithm that was generated to exploit the technical specificities (multiple oligonucleotides per probe set with perfect match and mismatch sequences) of the most commonly used microarray on the market.

Each SNP is interrogated in both the sense and antisense direction by multiple "quartets" of 25-mer oligonucleotide probes.

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