Sentence examples for multiple nucleotide changes from inspiring English sources

multiple nucleotide changes were not taken into account.

Another is multiple nucleotide changes in a codon.

Evidence for multiple nucleotide changes was found by Averof et al. [27], and the frequency of multiple nucleotide changes was evaluated [20].

Alternative explanation is that the significant fraction of these substitutions occurred with multiple nucleotide changes.

We have examined how the AIC is improved by enabling multiple nucleotide changes in a codon.

When multiple nucleotide changes are taken into account in the model ML-91, these discrepancies disappear and the AIC values significantly decrease, indicating the significance of multiple nucleotide changes in codon substitutions; see Fig. 1, Fig. S1, and Table 3.

To gain further insight into the impact of variable site removal and long-branch exclusion on saturation in our data matrix (i.e., the history of multiple nucleotide state changes at individual sites), pairwise genetic distances between all accessions were determined in MEGA4 [ 83] both without correction and with application of a Jukes-Cantor correction.

The matrix (m μν ) is parameterized with 9 parameters; one additional parameter (m) is needed to represent the ratio of multiple to single nucleotide changes.

The function of this region was further explored by well-established approaches such as (i) multiple mutagenesis (three nucleotide changes, F9mut1) or (ii) deletion (six nucleotides, F9ΔES1) (Fig.  2A).

In the present model, a nucleotide mutation rate matrix is fully parameterized by 8 parameters, and one additional parameter (m) is employed to represent the ratio of multiple to single nucleotide changes in a codon.

The DUF1220-encoding NBPF genes required the most corrections, with 3 genes removed, 2 genes reassigned to the 1p11.2 region, 8 genes requiring assembly corrections for DUF1220 domains (~91 DUF1220 domains were misassigned), and multiple instances of nucleotide changes that reassigned the domain to a different DUF1220 subtype.