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Visual function was assessed by measurement of the optokinetic response in cdh23 siblings and mutants.We detected cdh23 mRNA expression in multiple nuclei of both the developing and adult central nervous system.
This study aimed to optimise MALDI IMS for use on archived formalin-fixed-paraffin-embedded human infant medulla tissue (n = 6, controls; n = 6, SIDS) to evaluate differences between multiple nuclei of the medulla by using high resolution IMS.
At −900 mV (vs. Ag/AgCl), multiple nuclei of 2.0 3.0 nm in size were randomly distributed, even in nanopores with a 10 nm diameter, which could result in a lack of uniformity in the magnetic properties.
Microscopic examination revealed that worms carrying either mutant hcf-1 allele when grown at 12°C frequently display cells with multiple nuclei of heterogeneous size, extra spindle poles and improper spindle alignment; the embryos often stopped development at or prior to gastrulation (data not shown).
The most likely scenario that multiple nuclei of a heterokaryon could merge is the breakdown and reassembly of the nuclear envelope as the cell undergoes mitosis.
DOI: http://dx.doi.org/10.7554/eLife.00505.004 10.7554/eLiFigure05.005 Figure 1 figure supplement 2. Larger panels of chromatin spreads showing multiple nuclei of double mutants stained with S9.6 antibody.
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It's an amoeba-like, single-celled organism filled with multiple nuclei, part of a primitive lineage that's been munching on bacteria, fungi and other forest detritus for hundreds of millions of years.
Strong deregulation of cell proliferation by AP2C3 overexpression is also indicated by the presence of multiple nuclei in stomata cells of AP2C3oe plants.
During the generation of doxorubicin resistant MCF-7 clones, we observed the presence of multiple nuclei, in the enlarged cytoplasm of cells.
To test the hypothesis that Termitomyces is prone to nucleus-level selection, we performed competition experiments among multiple nuclei, using mixtures of homokaryons and following nuclear segregation in the asexual spores of heterokaryons.
We confirmed that the cultured cells had the morphological features of myotubes of multiple nuclei and longitudinal growth.
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