Sentence examples for multiple nucleases required from inspiring English sources

As mentioned above, SLX4 appears to coordinate the multiple nucleases required for ICL repair, including MUS81 EME1 and the nucleotide excision repair endonuclease XPF ERCC1.

Targeted integrations into chromosomal breaks, created by nucleases, require large transformation efforts.

Deletion of regulatory elements by ZFNs, TALENs, or CRISPR nucleases requires targeting functional nucleases (heterodimeric in the case of ZFNs or TALENs or monomeric in the case of CRISPR nucleases) to both sides of the element.

Thus, the subsequent analysis of mutant organisms obtained using engineered nucleases requires powerful techniques for large-scale mutation detection.

Multiple nucleases have been identified to catalyze fragmentation of chromosomal DNA during apoptosis.

Ideally, the authors would have done some kind of an RNase protection assay in vitro, possibly with multiple nucleases, to establish the certainty of their results.

It is possible that in S. pombe, as well as in higher eukaryotes, multiple nucleases are involved in the endonucleolytic unhooking step of ICL resolution.

When multiple conditions are required, multiple independent experiments are run.

Are multiple mutations required?

These structures unify Mre11's multiple nuclease activities in a single endo/exonuclease mechanism and reveal eukaryotic macromolecular interaction sites by mapping human and yeast Mre11 mutations.

DinG serves as a helicase partner for multiple nuclease domains such as the RNase T-like and RNase D-like nuclease domains (both of which belong the RNAse H fold) [ 45- 47].