Sentence examples similar to multiple new mutations from inspiring English sources

The segregating sites analysis revealed multiple new mutations-a pattern also indicative of a recent population expansion (which initiated at ~23,000-32,000 BP).

While natural selection operates on the genetic combinations created by sex, the writing of mutations combines information from multiple loci into new mutations, which are not themselves broken by the sexual shuffling, and thus allows the combinations to have hereditary effects according to their fitness.

Based on a careful observation of the structure of the C-domain of ACE (12), we predict that the R828H mutation may induce multiple new interactions with residues of the 840 loop region which could contribute to the misfolding of the protein by the disruption of the helical (α8) structure and the salt bridge (R829 E1188) stabilizing the C-terminal loop (Fig.  7B, 1 and 2).

Some of the rare variants may be relatively new mutations and may affect multiple patients of unknown relationship in a given population.

New mutations cause the simultaneous presence of multiple subclones of cells at different malignancy levels, all sharing a common ancestor, which leads to tumor heterogeneity [ 129].

One scenario indicates that the same original clone exists at diagnosis, while the other suggests that multiple subclones exist that were derived from the original clones with new mutations.

Because all mutations are mapped onto a multiple sequence alignment, analogue positions between kinases can be identified and tentative new mutations can be proposed for studying by transferring annotation.

The mutation frequency in C. elegans is low (~0.3 1 new mutations per progeny [ 31, 32]), suggesting that the problem of multiple mutations per progeny might not be of practical relevance – quantification of mutation distributions in progeny from old hermaphrodites could confirm this or provide data to guide modifications to the performance objective.

When a single mutation in a subscriber (or publisher) shifts to the matching signal, multiple new connections are formed.

These results again show that coinfection by multiple quasispecies is not uncommon in human tissues, and that passage to Vero cells may either generate new mutations at a low rate, or titrates out one quasispecies in the transition.

DNA sequence comparisons with multiple primate species have revealed near-conservation of alleles at variant loci in humans providing conclusive evidence that new mutations are quickly eliminated.