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Although multiple new agents have been approved for metastatic castration resistant prostate cancer over the last decade, it is still an incurable disease.
However, the agent-based thinking challenges resurfaced in activity 5 when the students were required to model multiple new agents, and modeling multiple agents caused the number of challenges to increase sharply.
It is suggested to perform multi-arm randomized selection design where multiple new agents are compared to each other with the agent showing the best clinical effects chosen to be tested further.
Since then, multiple new agents targeting this pathway have been developed and are in clinical use.
Multiple new agents with immunomodulatory effects have been investigated in recent years but limited success has been achieved.
The development of multiple new agents for the treatment of type 2 diabetes has broadened the options for patient-specific therapy.
Similar(52)
The need to test multiple new targeted agents both alone and in combination with other targeted therapies, as well as classic cytotoxic agents, demands the development of novel therapeutic platforms (particularly Master Protocols) capable of efficiently and effectively testing multiple targeted agents or targeted therapeutic strategies in relatively small patient subpopulations.
Recently, multiple new chemotherapeutic agents have been developed and some are in clinical trials [ 2, 3].
This may be particularly relevant to efforts to improve trial efficiency in order to test multiple targeted new agents in combination.
Since 2005, treatment of metastatic RCC has undergone a remarkable transformation with the availability of multiple effective new agents including VEGF-R TKIs, mTOR inhibitors, and anti-VEGF monocolonal antibody in combination with interferon.
Multiple newer biologic agents targeting specific immune system pathways and effectors are undergoing evaluation [ 94].
More suggestions(15)
multiple new agreements
multiple new faces
multiple pharmacological agents
multiple new imprints
multiple new investments
multiple new devices
multiple new points
multiple new invasions
multiple mobile agents
multiple new workers
multiple new samples
multiple new concepts
multiple new products
multiple new apps
multiple new directions
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com