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Genetic studies have focused on investigating genetic variability in multiple neurotransmitter systems which interact and overlap at different levels.
Since multiple neurotransmitter systems within the CNS can be implicated in sleep disturbances in schizophrenia, the characterization of the neurotransmitter systems involved remains a challenging dilemma.
Variation in Comt message and protein levels caused by the B2 SINE influences multiple neurotransmitter systems, and has known and novel downstream effects on neuronal signaling and behavior (Fig. 7).
CINV is an autonomic reflex controlled by multiple neurotransmitter systems.
The neurobiology of nicotine addiction is complex and involves interactions between multiple neurotransmitter systems.
A multitude of morphine effects indicates that multiple neurotransmitter systems are involved in formation of each behavioural profile.
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Spontaneously active neuronal networks reflect the interactions of multiple neurotransmitter and receptor systems, and can reveal unexpected side effects due to secondary binding.
Maturation of the mammalian cerebral cortex is, in part, dependent upon multiple coordinated afferent neurotransmitter systems and receptor-mediated cellular linkages during early postnatal development.
The circadian rhythm, including the maintenance of sleep and wakefulness, involves a complex network with multiple nuclei and neurotransmitter systems.
The ability of dietary manipulations to evoke widespread changes in neuro transmitter function is likely due to changes in the composition of membrane lipids in which receptors and cell signaling molecules are embedded (Gudbjarnason and Benediktsdottir 1996; Ponsard et al. 1999) and therefore can span multiple brain regions and neurotransmitter systems.
When rats are administered multiple doses of MDMA, different neurotransmitter systems come into play and there is the further inhibitory effect of noradrenaline," says Sumnall.
More suggestions(15)
multiple chaperone systems
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