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The glycans on the MUC2 mucin from human colon carries multiple negative charges on both sialic acid and sulfate residues [19].
This again suggests involvement of minigastrin's multiple negative charges in its renal reuptake.
The presence of divalent Ca2+ ions alters the free counterion distribution and introduces ion bridging between multiple negative charges.
If the radiotracer contains multiple negative charges (e.g., two D3 linkers in 99mTc-P6D-RGD2 99mTc-P6D-RGD2 99mTc-P6D-RGD2iothecer and albuminteractionme significant.
This study sought to evaluate the impact of multiple negative charges on blood clearance kinetics and biodistribution properties of 99mTc-labeled RGD peptide dimers.
It was concluded that the multiple negative charges have a significant impact on the blood clearance kinetics and tumor uptake of 99mTc-labeled dimeric cyclic RGD peptides.
Similar(50)
We evaluated the ternary ligand complexes [99mTc(HYNIC-P6G-RGD2)(TPPTSne)(TPPTS)] and [99mTc(HYNIC-P6D-RGD2)(TPPTSne)(TPPTS)] (99mTc-P6D-RGD2) in the athymic nude mice bearing U87MG glioma xenografts to explore the impact of multiple negative overall molecular charges on blood clearance kinetics and biodistribution properties of 99mTc radiotracers.
These surface molecules carry negative charges that inhibit adhesion between cells or negatively charged surfaces.
Multiple points on myosins may coordinate actin filament association including surface loops and positive or negative charges.
+ and – signs represent positive and negative charges.
Thus, two negative charges repel one another, while a positive charge attracts a negative charge.
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