Sentence examples for multiple myeloma only from inspiring English sources

Johnson & Johnson, for instance, agreed to charge for Velcade, another drug for multiple myeloma, only if tests showed it was effective in a particular patient.

The proteasome inhibitor bortezomib is an FDA-approved drug for the treatment of multiple myeloma, but has shown only little single-agent activity in solid malignancies such as HNSCC while being effective in combination with other treatment options.

In any case this pilot study provides initial evidence that the TNF/TNF receptor system is not only active in multiple myeloma but also of significance for the course of the disease.

28 Multiple myeloma causes only osteolytic lesions.

Curcumin anti-tumor effects were previously characterized in multiple myeloma, however only few MM cell lines were included in these studies.

Interestingly, the cancer type that displayed the lowest number of hypermethylated PRC2 targets was multiple myeloma, the only non-solid tumor analysed, despite having the second highest number of differential methylation sites (below colorectal cancer) (Table 1 and Figure 5).

Previous reports showed that not only multiple myeloma cells but also BMSCs adherent to multiple myeloma cells also release IL-6 via NF- κB pathway to support MM cell growth [ 25].

These FLC assays have a particular role for the diagnosis and monitoring of light chain only multiple myeloma [ 1], but in addition their sensitivity has lead to the development of a new classification of response of multiple myeloma: stringent complete response (when the FLC ratio has normalised, in addition to standard parameters).

Several drugs have been approved as second-line therapies for multiple myeloma (agents administered only when initial treatments have been determined to be ineffective); examples include pomalidomide, which modulates immune activity, and carfilzomib, which inhibits the degradation of certain proteins in cells and may thereby prevent further tumour growth.

However, the role of microRNAs in the pathogenesis of multiple myeloma (MM) is only poorly understood.

109 Lenalidomide appears to be less neurotoxic and better tolerated than thalidomide at a dose of 30 mg/day in relapsed/refractory multiple myeloma patients, with only 3% of significant grade 3 neurotoxicity after the completion of chemotherapy.