Sentence examples for multiple mutation tests from inspiring English sources

In our study, combination of multiple mutation tests (KRAS or BRAF± PI3KCA) did not provide additional information over a single mutation test (data not shown).

Single-gene testing is unlikely to be clinically useful for prognosis; although MSI immunohistochemistry is becoming routine and may confer prognostic significance in certain scenarios 28, it is notable that multiple mutations are tested simultaneously.

Across the collection of these mammals, there has been ~2.9 billion years of evolution, which ensures that a vast majority of sites in the genome have been evolutionarily tested on multiple mutations, given that the mutation rate is of the order of 10−8 10−9 per base per year37,38.

If alleles carry multiple mutations, you may need to perform site-directed mutagenesis to create single amino acid substitution alleles and test their ability to confer drug resistance.

Adaptive evolution of multiple traits through multiple mutations at a single gene.

Many human diseases are caused by multiple mutations.

According to section 'Fault-based testing and mutation testing', mutation testing [41] is a largely explored fault-based criterion.

Complete reversion to virulence would be detected during safety testing and such lots would be eliminated, but if attenuation is enacted by the epistatic effect of multiple mutations (Burch et al. 2003), and a subset of these are lost during vaccine manufacture, then complete reversion would require fewer subsequent mutations.

This technology also has the capability to correct multiple mutations simultaneously, which will be crucial to curing diseases that arise by more than one genetic mutation.

Chronocoordinate multiple mutations that span multiple kilobases [9].

Are multiple mutations required?