Sentence examples for multiple mutation hits from inspiring English sources

Soares et al. (2009), however, did not correct for multiple mutation hits and, in addition, the distance was erroneously underestimated (Pedro Soares, personal communication).

The observed human-chimpanzee distance of 860 synonymous transitions was used to test the applicability of the 3-rates model of synonymous sites for the correction of the genetic distance for multiple mutation hits.

2. Multiple hits: To the extent that multiple mutations hit the same gene or pathway, subsequent mutations will more likely be neutral than initial ones, because the same function cannot be destroyed twice.

Co-occurrence of multiple mutations (including double hits to the RAS-pathway) was observed at a higher frequency within MC (26/37; 70.3 %) over MBOT (12/26, 46.2 %), however was not statistically significant (Fisher exact test p = 0.0634).

There are 10 mutations stored in YDHS database for R1b1a2 haplogroup and interestingly only one mutation hits a gene region, namely eukaryotic translation initiation factor 1A (EIF1AY).

Complex traits can require the accumulation of multiple mutations that are individually deleterious.

Adaptive evolution of multiple traits through multiple mutations at a single gene.

"We already have the technical capabilities to assess men for multiple mutations at once, so all that remains is for us to do further work to prove that picking up dangerous mutations early can save lives.

While recombination can bring together multiple mutations within an organism, evolution in asexual populations depends on the sequential accumulation of mutations within a lineage.

This technology also has the capability to correct multiple mutations simultaneously, which will be crucial to curing diseases that arise by more than one genetic mutation.

Chronocoordinate multiple mutations that span multiple kilobases [9].