Sentence examples for multiple mutants in from inspiring English sources

The calculated stability score shows good correlation with the measured thermal stability for 76 single point mutations and 22 multiple mutants in β1AR.

Simultaneous survivals were then conducted for multiple mutants, in parallel with their isogenic wild-type controls.

The STM technique allows for the simultaneous screening of multiple mutants in mixed populations by detecting unique DNA tags.

Hence, we conducted a genetic screen and isolated multiple mutants in which GFP RAB-3 lost its punctate localization pattern.

This yielded multiple mutants in the Fgf/Erk and GSK3/Tcf3 modules known to drive differentiation and in epigenetic modifiers implicated in lineage commitment.

Furthermore, we cloned each putative miR-1290-target miR-1290-target miR-1290-target their siteences thavingrresponded to the "seed sequence" of multiple into the pmutantsort plasmin and performed reportheirsequences

Multiple mutants, defective in synthesis of ChoD, HsdD and ketosteroid dehydrogenase (KstD), showed attenuated growth in minimal medium supplemented with cholesterol and accumulated cholesterol degradation intermediates: androstendion (AD) and 9-hydroxy androstendion (9OHAD).

This limited collection of mutant PAI-1 preparations contained multiple mutants defective in binding to three out of four tested anti-PAI-1 monoclonantibodiesies.

In the last instance, the rpoB multiple mutants were selected in vitro in a stepwise fashion, and one double mutant, L511Q+D516G (also described in M. tuberculosis strain [ 3]), exhibited a relative fitness either greater than or equal to either single mutant or the wild type.

Even so, we obtained quintuple genome modified cells by transient expression of CRISPR/Cas9, and the multiple mutants grew poorly in axenic medium (Fig. 5B), as expected9,26.

However, the changes in ribosome profiles and rRNA structures in multiple mutants suggest the intriguing possibility that they may each contribute to refining the structure and function of the translational apparatus.