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While we have tested multiple mutants affecting pharyngeal muscle integrity, the effects of these mutations on gland morphology may not occur via a single mechanism.
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Mutants affecting this trait have been characterised.
To determine whether the mutants affected repression of multiple miRNA targets, we assayed the expression of a LacZ reporter transgene that was under control of the E spl m8 3′UTR.
Four of these new mutants affect both eyecolor and chromosome segregation.
The multiple mutants showed denaturation temperatures up to 27 deg.
There, the pollen grains from tir1 and afb1afb2afb3 multiple mutants age prematurely (Cecchetti et al. 2008).
For this study, we generated multiple mutants of STBD1.
Moreover, neither U2 snRNA mutant affected the 6-AU sensitivity of the double mutant.
There are multiple paths; multiple mutations affecting multiple cellular systems make significant contributions.
Normal mosue embryo (left) and mutant mouse embryo (right) resulting from a targeted mutation affecting development in multiple tissues.
Indeed, the indeterminate phenotype of the yuc4 mutant was only observed in the sensitized yuc multiple mutant background25.
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