Sentence examples for multiple mutant haplotypes from inspiring English sources

Our method enables the inference of fitness of multiple mutant haplotypes arising in an experiment, with no prior assumption of their distribution of fitness effects, while also allowing for the detection of standing variation in the initial pool.

Analysis of flanking microsatellites suggests multiple independent introductions for dhfr and dhps mutant haplotypes, possibly from West Africa.

Among the multiple mutant phenotypes, pathogenicity-defective mutants were our primary focus in this study.

These findings are consistent with positive selection on mutant haplotypes, presumably caused by sulfadoxine pressure.

Furthermore, the compositions of mutant haplotypes are quite different between Caucasian and Japanese individuals.

While multiple measures of evolvability can be calculated (Barrick et al., 2010), in our case the mean fitness of the first mutant haplotype observed for each population was considered.

Because all fragrant varieties seem to contain the same mutant haplotype, fragrant rice is inferred to have arisen once.

The selective advantage of alleles and haplotypes were quantified with selection coefficients: Selection was positive on all mutant alleles and haplotypes associated with SP resistance, and the relative fitness of the quintuple mutant haplotype was 0.139 955% C.I. 0.067 0.211), indicating a substantial positive selective advantage.

The multiple mutants showed denaturation temperatures up to 27 deg.

In the symptomatic group 96% of parasites carried the triple dhfr mutant haplotype (mutants at codons 51, 59 and 108) (Table 4) showing near saturation of this haplotype.

First, these data suggest that the S GEG haplotype may arise where a S GEA haplotype is circulating without requiring the importation of a new mutant haplotype.