Sentence examples for multiple mutant forms from inspiring English sources

Utilizing multiple mutant forms of yeast Rfa2, specific subregions of the Rfa2 NT important for the damage response were identified.

We are currently examining if multiple alanine mutant forms of cdc25C disrupt mitosis in more transformed cells.

It should also be noted that levels of the full-length APP were not altered in BACE1+/−·5XFAD mice, suggesting that merely overexpressing multiple FAD mutant forms of APP is unlikely to cause cholinergic or cognitive defects in 5XFAD mice.

Significantly, the Asp101 side chain of our highly active double mutant forms multiple stabilizing interactions with neighboring amino acids (Fig. 4a), even though this residue does not naturally occur at position 101 among orthologs of our bioinformatics analysis (Fig. S1).

While the i-PITT can be used for generating any type of transgenic mice, this technology will be particularly suitable for simultaneously generating Tg lines for multiple different polymorphic variants or mutant forms of a gene.

ERPO may represent an ER quality control pathway for multiple ER substrates, since aggregation-prone mutant forms of seipin that are associated with an autosomal dominant motor neuron disease, accumulate in the same compartment [ 27].

Multiple transgenic stocks expressing wild type and mutant forms Lamin C were tested to rule out effects due to the site of insertion (Table S2).

When we initially selected for imatinib-resistance of mutagenized BCR/ABL in bulk liquid culture, we found only 4 mutant forms that were represented multiple times within the first 100 isolates we sequenced.

Protein localization and aggregation were quantified for wt and mutant forms of RUNX2 by analyzing multiple 350 × 350 µm microscopy fields (n ≥ 10) from at least three different coverslips of cells transfected in distinct experiments.

This interactome is of high quality because the database was constructed of multiple screens of 9 cDNA libraries using wildtype and mutant forms of G protein baits.

These mutant forms hark back to Bosch's apocalyptic visions of disorder and self-destruction.