Sentence examples for multiple mutant alleles from inspiring English sources

Alternatively, a comprehensive set of temperature-sensitive mutants for essential genes [42], including multiple mutant alleles of the same gene, may provide intragenic insights into the inhibitory mechanisms of compounds even if the target genes are multifunctional (e.g., FKS1 [35], [35]).

Multiple mutant alleles of Tjp1a clearly demonstrate an essential function in metamorphic stripe formation.

Additional experiments are necessary to test this hypothesis such as identifying multiple mutant alleles of Pgd3.

Whether the same is true for other multiple mutant alleles in M. tuberculosis rpoB remains to be seen.

The experiments are very rigorous and thorough, employing multiple mutant alleles, RNAi lines, transgenes, antibodies and biochemical reagents.

A total of 71 mutations were identified by TILLING, providing multiple mutant alleles for every gene tested.

61 X-ray crystallographic analysis of multiple mutant ABL alleles in imatinib-resistant patients was essential for the screening and development of second-generation TKIs.

The sugar- and ABA-insensitivity of multiple abi3 mutant alleles show a strong positive correlation in our assays.

In both sets of experiments, flies corresponding to multiple independently generated yar mutant alleles were tested.

We identified that multiple loss of function mutant alleles of the Arabidopsis HOMOSERINE KINASE gene DMR1 have increased resistance to Fusarium culmorum: Siliques of dmr1- 2, dmr1- 3, dmr1- 4 and dmr1- 6 were found to be more resistant to infection and leaves of dmr1- 1, dmr1- 2, dmr1- 3 and dmr1- 4, supported reduced leaf colonisation.

We characterized 14 spn-E mutant alleles using multiple phenotypic criteria and identified point mutations in the spn-E gene in these alleles.