Sentence examples for multiple murine studies from inspiring English sources

The observation that aging is associated with mortality has been replicated in multiple murine studies of sepsis [ 4, 5], and it has been suggested that using young mice as surrogates for older patients is one of many reasons why positive preclinical trials in sepsis have failed to translate into therapeutic benefit at the bedside [ 6].

- Also, multiple murine studies have observed that survival of the peripheral T cell compartment is dramatically reduced in the absence of autophagy., In contrast to mature T cells, mature peripheral B cells do not require autophagy for survival, as demonstrated in Atg5 −/− mice, and do not have detectable levels of basal autophagy.

The microarray results confirm that canine miRNAs hybridize with multiple murine targets, which facilitates studies using veterinary samples.

Studies in multiple murine SLE models point to an essential role for the IL-6 pathway in SLE.

Murine studies indicate that multiple injections with smaller volumes may be optimal.

To further complicate matters, murine studies have identified multiple pluripotent states that are maintained by different signalling networks [ 22].

Multiple murine models have proven useful in studying the natural history of neovessel development in the tissue engineering of vascular grafts.

Several human and murine studies that are not included in the IPA Knowledge Base® have demonstrated activation of multiple kinases and transcription factors including the MAPKs MEK1/ERK1/2, p38, the PI3K/AKT/mTOR axis, the NF-kB and multiple Bcl-2 family members, and the Jak/STAT pathway [14] [19].

Here we demonstrated that PAb induced apoptosis in multiple murine myeloma cell lines was accompanied by the usual hallmarks of apoptosis as revealed by microscopic study of changes in cell morphology, DNA laddering, and flow cytometry (Fig.  3).

Taken together, human and murine studies demonstrate the immunologic potential of the esophagus.

Bhattacharyya, J. et al. A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms abraxane in multiple murine cancer models.