Sentence examples for multiple murine models from inspiring English sources
Multiple murine models have proven useful in studying the natural history of neovessel development in the tissue engineering of vascular grafts.
One important advance in understanding the pathogenic mechanisms of this disease has been the development of multiple murine models that replicate many of the clinical, neuropathological, and molecular events in HD patients.
In line with the implication of GSK-3β-activated pathways in disease pathogenesis, TDZD-8 has been shown to be a protective agent in multiple murine models of disease such as arthritis, spinal cord injury, colitis, and septic shock [13], [14], [15], [16], [17].
NGAL was elevated in multiple murine models of obesity, and reduction of NGAL in cultured adipocytes improved insulin sensitivity.
Multiple murine models indicate a pivotal role of IL-21 in the pathogenesis of autoimmune diseases [ 7- 9].
Since OA is thought to be a multifactorial disease, it is necessary to use multiple murine models to best understand OA disease progression.
Studies in multiple murine SLE models point to an essential role for the IL-6 pathway in SLE.
This combination resulted in significant survival improvements in multiple murine tumour models, including breast and ovarian cancers, and was well tolerated.
Multiple murine experimental models have shown that NPD1 ameliorated damaging pathology in corneal injuries, oxidative-stress-induced retinal epithelial pigmentation, and brain cells exposed to β-amyloid.
In a previous work, we have shown an influence of the microenvironment on tumour cell in the 5T2 multiple myeloma murine model, as a high bone remodelling (induced by ovariectomy) dramatically increased tumour growth (Libouban et al, 2003).
Over the last five decades, several different types of murine models of multiple myeloma have been developed ranging from immunocompetent syngeneic models, e.g. the 5T series of myeloma cells, to immunocompromised models including the SCID xenograft models, which use human myeloma cell lines or patient-derived cells.
