Sentence examples for multiple motifs and from inspiring English sources

Our pipeline uses GADEM [20], which is a good compromise between fully probabilistic and enumerative approaches, can process large sets of ChIP-Seq regions, handles both dimer and monomer motifs, automatically identifies multiple motifs, and automatically adjusts motif widths.

A common strategy in motif interactions is the co-operative binding of multiple motifs and motif-binding domains, which in isolation are somewhat promiscuous, to mediate highly specific interactions.

For clarity, we will explain our method by limiting to only one motif in the sample, and every sequence contains at least one occurrence d-mutant of the motif even though our method can deal with multiple motifs and 10-20% of contamination.

The cluster in left contains drug-centered motif (red circles) and multiple motifs (purple squares), and the lower cluster in right comprises target-centered motifs and multiple motifs and the upper cluster in right is composed of all four types of motifs.

Then, the recall and the precision are computed as A low SN statistic indicates the lack of ability to discover planted multiple motifs and a low PPV statistic can be a signal for less identification accuracy, for instance the occurrence of over- or under-estimates of the planted motif regions.

This yielded multiple motifs for some TFs and none for others, and some motifs were associated with TF families rather than individual TFs; thus, our analysis was based on "motif sets" that share a common annotation, rather than individual motifs.

Redundant TF sites were removed (for example a generic SMAD site and a SMAD3 site mapped to the same location were counted as one site) and multiple motifs for each TF were collapsed down to a single motif (for example AP1.01 and AP1.02 were reduced to AP1).

In this study, we designed the peptides with multiple motifs composed of RGD and its analogs to induce integrin-mediated endocytosis as well as endosomal escape by forming an amphipathic helix in acidic endosomes.

In detail, (1) for multiple motifs), known interactions (purple) and unapproved DTPs (cyan) can be separated significantly by C t w, moderately separated by either C t b or C d w, and almost mixed together in terms of C d b. (2) For drug-centered motifs whose C d w is unavailable), C t w, C t b, and C d b show the best, the moderate, and the worst separations, respectively.

Counting the number of sequences (not occurrences) is equivalent to the 'Zero or One Occurrence Per Sequence' (ZOOPS) model used by numerous motif discovery algorithms, and finding multiple motifs by erasing is reminiscent of MEME (Bailey and Elkan, 1995).

We use the same approach to adopt traditional promoter scanning to handle multiple motif models and report the smallest p-value over the multiple motif models.