Sentence examples for multiple molecules involved from inspiring English sources

Catecholamines can stimulate the expression of multiple molecules involved in tumor cell proliferation, migration, invasion, adhesion, and metastasis, influencing biological behaviors of tumor cells [ 23].

To elucidate drug response in EGFR signal transduction pathway in which complex dynamics of multiple molecules involved, a systematic approach is necessary.

The EMT phenomenon seems to be promising because multiple molecules involved in EMT, such as receptor- and SRC-family tyrosine kinases, RAS and other small GTPases, can be envisioned as targets for anti-EMT therapy [ 58].

Chronic lead exposure results in decreased nitric oxide and impaired nitric oxide signaling, alterations in vasoactive prostaglandins, alterations in the renin angiotensin system, and alteration of multiple molecules involved in endothelial and vascular function in vitro and in vivo in rats (Rodriguez-Iturbe et al. 2005; Vaziri 2008).

Binding of FGF and especially VEGF, which is considered a major molecule controlling blood vessel morphogenesis, to their tyrosine kinase receptors activates multiple downstream molecules involved in different signalling pathways that lead to increased vascular permeability, cell migration and proliferation [3].

So there may be multiple signal molecules involved.

To better understand inhibitory effects of ellagic acid on VEGFR-2 and its downstream signaling, we next chose multiple essential downstream signaling molecules involved in VEGFR-2 activation for western blotting detection.

Noncoding RNAs, including microRNAs and long noncoding RNAs (lncRNAs), are key regulatory molecules involved in multiple cellular processes.

As a result, these cytokines can now be regarded as important autocrine/paracrine signaling molecules involved in multiple steps of CNS development.

This analysis revealed increased expression of signalling molecules involved in multiple cellular processes and physiological functions including normal development or stem cell maintenance and pathogenic conditions in humans such as tumorigenesis and cancer.

However, combination strategies inhibiting molecules involved in crosstalk between multiple pathways have potential to induce conditional lethality (Carver et al, 2011; Azad et al, 2015c).