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Flow cytometry is known as an excellent phenotyping tool, because multiple molecules, surface markers as well as intracellular proteins, can be detected in individual cells [ 6].
Given the fact that many factors participate in the governance of the fate of melanoma cells, it is worth targeting multiple molecules in different pathways as a therapeutic approach.
This database also contains molecular complex modules, comprising multiple molecules such as the subunits of transporters and receptors, functional sets, and signature modules.
This response involves multistep processes and multiple molecules, such as DNA-dependent protein kinase (DNA-PK), ataxia telangiectasia-mutated (ATM) kinase, Kruppel-associated protein 1 (KAP1), complementation group D2 (FANCD2), XRCC2, and XRCC4 [ 10, 49, 54].
So it is not surprising to find that many in vivo and in vitro studies showed decreased levels of multiple molecules from different organs, such as nuclear factor kappa B (NF-κB), inducible nitric oxide synthase (iNOS) [ 18], caspases [ 19], reactive oxygen species [ 20], hypoxia inducible factors (HIFs) [ 21], and pro-inflammatory cytokines [ 22].
Furthermore, LDL can act as a magnet that attracts multiple molecules of HNE over time.
These compounds have been designed as odourless and tasteless pro-drugs which will release multiple molecules of cysteamine upon administration.
In summary, this work provides the first evidence that boundary-derived FGF signaling, in particular FGF3, regulates the expression of multiple molecules responsible for ECM integrity, as well as genes involved in neuronal differentiation and axonal organization at boundary cells, and thus contribute to the understanding of how boundary-unique properties arise.
Nonbonding π or d orbitals of a single molecule (or multiple molecules) can function as quantum dots, where the electric charge is localized in each cell.
Using the plaque reduction assay, relatively simple bicyclic quinone molecules, as well as multiple copies thereof covalently attached to a long polyglutamate‐based polymeric chain, were examined as new inhibitors of various naturally occurring strains of influenza A virus.
In the case of CREB, multiple molecules or proteins, such as CGRP [9], lead to its phosphorylation, via activation of several kinases [1, 30 32].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com