To develop potent and selective MMP-2 inhibitors, initially multiple molecular modeling techniques were adopted for robust design.
Development of high-quality upconversion nanoparticles (UCNPs) with combination of the merits of multiple molecular imaging techniques, such as, upconversion luminescence (UCL) imaging, X-ray computed tomography (CT), and magnetic resonance (MR) imaging, could significantly improve the accuracy of biological diagnosis.
The protocols are most useful for complicated assays like the Haplotype-specific Chromatin Immunoprecipitation, where multiple molecular biology techniques has to be carried out and the fine-tuning of experimental parameters vital to eventual success.
Multiple molecular imaging techniques have been used not only to monitor complex biological processes both spatially and temporally but also to study the transplanted cell trafficking, long term monitoring of disease (i.e., cancer progression), and therapeutic effectiveness in living animals [ 1, 2].
Detection of the larval stage of this pathogen in an unusual host in a new geographic region required application of multiple molecular epidemiologic techniques to determine if this was range expansion of a native strain or introduction of a new strain of veterinary and public health concern.
Multiple studies using molecular techniques or strict anoxic culture have demonstrated anaerobic bacteria in CF airway samples, including during pulmonary exacerbations [4], [5], [12], [14], [33], [34].
Studies of multiple closely related cases by molecular techniques such as SNP-based association mapping [ 9] would probably be most helpful in demonstrating a genetic aetiology.
Recent investigations using molecular techniques have identified multiple obligate bacterial endosymbionts in Cicadomorpha; however, much less is known about endosymbionts of Fulgoroidea.
The molecular architecture of presynaptic active zones has been revealed using super-resolution microscopy techniques that combine nanoscale resolution and multiple molecular identification.
With the advent of molecular techniques, independent data became available and multiple molecular markers have now been employed to attempt to resolve the crested newt phylogeny.
