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Using this device, the mechanokinetics of multiple molecular motors or adhesion proteins may be measured simultaneously.
The microtubule cytoskeleton is reorganized to form a bipolar spindle between duplicated microtubule organizing centers, the chromosomes are condensed, attached to the spindle at their kinetochores, and, through the action of multiple molecular motors, the chromosomes are segregated into two daughter cells.
The squid genome is not yet available, however, it has been shown to contain multiple molecular motors including cytoplasmic dynein and members of the kinesin superfamily of proteins, which exhibit high degree of similarity to the mammalian ones (Degiorgis et al., 2011).
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We hypothesize that flexible motor linkers might facilitate collective transport driven by multiple copies of molecular motors in living cells.
Further molecular research showed that two similar molecular motors KIFC1 and KIFC5 were associated with multiple microtubule complexes in male germ cells, including the meiotic spindle, the manchette, and the flagellum [47], with important roles.
Multiple Ca2+-dependent steps have been elucidated so far, involving molecular motors, cytoskeletal elements and SNARE proteins that finally lead to the formation of a fusion pore, an elusive, channel-like structure that represents the initial connection between vesicle lumen and extracellular space [3] [8].
Molecular motors push particles along the tubes.
The Feringa group used molecular motors in more ambitious projects.
Work this year captured molecular motors in motion.
Moving along microtubules, mitochondria are transported by molecular motors.
Popular molecular propagation mechanisms include the use of molecular motors [17 19], bacteria [20, 21], and molecular diffusion [22, 23].
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