Sentence examples for multiple modification sites from inspiring English sources
The amyloidogenic tau protein represents another prominent example with multiple modification sites.
In addition, nuclear proteins such as histone and Npl3p are known to have peptides with multiple modification sites but these were not searched for in this study.
Library search methods can also be problematic for peptides with multiple modification sites, because it is unlikely that all the relevant permutations are present in the library.
The identification of multiple modification sites, together with a single SopB-Ub band on SDS-PAGE gels, suggests that SopB is mono-ubiquitinated on any one of six lysine residues at once, but not all six residues simultaneously.
Proteomics research has shown that several subunits of the enzymes in the mitochondrial ETC and TCA cycle have multiple acetylation modification sites, and increased acetylation was observed in Sirt3−/− tissues, indicating that the enzyme activities may be regulated by Sirt3.
Multiple post-translational modification sites have been observed, yet there are still many unanswered questions regarding the precise roles of these modifications in controlling the contradicting functions of E2F1.
However, it does not allow web-based batch processing of thousands of modification sites from multiple proteomics experiments.
Multiple modification variants were detected on 6 sites (14.6%), with a maximum of four different modifications per site.
The lack of a rigid 3D structure in IUPs is thought to provide several functional advantages, including conformational flexibility to interact with multiple targets, increased interaction surface area, and accessible post-translational modification sites [ 4, 5].
Multiple alignment of protein sequences and visualization of the detected post-translational modification sites were performed using CLC Sequence Viewer (CLC Bio).
Since the protein binding or histone modification sites are represented as genomic intervals, such task requires the comparison of multiple sets of genomic intervals.
