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For GPCRs, allosteric mechanisms impart multiple modes of target modulation (positive allosteric modulation (PAM), negative allosteric modulation (NAM), neutral cooperativity, partial antagonism (PA), allosteric agonism and allosteric antagonism).
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Target-site resistance confers resistance to a single herbicide mode of action, whereas non-target-site resistance may result in complex patterns of cross-resistance rendering populations resistant to multiple modes of action (Powles and Yu 2010).
Once multiple modes of transport are added in the likes of New York City, Tokyo, London and Paris, the visitor can be justifiably baffled.
They swap contexts frequently and rapidly during a typical day and use multiple modes of communication.
"Many will take multiple modes of inadequate transportation just to cast a ballot.
Design for multiple modes of teaching and learning in the classroom.
The young adults used multiple modes of communication including aided and unaided AAC approaches.
Apparently, DEET has multiple modes of action.
The cell-phone microscope can work in multiple modes of operation, including polarized and transmission modes.
Potential for contributions from multiple modes of action.
Tramadol is a unique drug with multiple modes of action.
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