The most common defect observed was multiple mitotic spindle poles rather than the expected bipolar structure.
Polo-like kinase 1 (plays plays key roles in regulating various mitotic processes that are critical for cellular proliferation.
Polo-like kinase 1 (plays plays key roles in regulating mitotic processes that are crucial for cellular proliferation.
Tim depletion caused multiple mitotic defects, including the loss of sister-chromatid cohesion, loss of mitotic spindle architecture, and a failure to exit mitosis.
Apparently, the multiple mitotic functions of SUMO carried out by the single SUMO isoform in Drosophila have been divided among multiple SUMO isoforms in vertebrates.
Soon after their formation, trimera-derived tetraploids undergo mitotic missegregation events involving multiple mitotic spindles.
It seems plausible that the combined action of multiple mitotic, Cdk1-regulated, factors fine-tune mitotic exit.
Our gene expression landscape showed two distinct modules (mitotic checkpoint and mitotic progression) that both contained genes related to central mitotic processes.
A strong anisocytosis, numerous cells with multiple nuclei, anisokaryosis, multiple mitotic figures, to some extent atypical mitotic figures, and a varying nucleus: plasma ratio could be detected.
For example, polo-like kinase 1 (Plk1) is a well-studied mitotic kinase whose inactivation leads to multiple mitotic defects and cell death.
