Sentence examples for multiple mitochondrial enzymes from inspiring English sources

26 Accumulation of 2-methacrylyl-CoA has been considered as toxic compound in HIBCH deficiency, a disorder of the fifth step of valine oxidation with Leigh-like neurological phenotype and combined deficiency of multiple mitochondrial enzymes (Fig. 1).

Mitochondria from SOD2−/− mice accumulate superoxide in their matrix space which oxidizes and damages multiple mitochondrial enzyme complexes, leading to decreased oxygen uptake and ATP production and lowered complex II activity [ 8, 9].

It is believed that the role of phosphorylated ubiquitin is to interact with Parkin, thus releasing Parkin's autoinhibitory domain [ 19] and exposing the ubiquitin ligase active site, allowing the enzyme to ubiquitinate multiple mitochondrial proteins [ 20].

While some mitochondrial enzymes activities were 25 49% lower in skeletal muscle of patients treated in the ICU for sepsis induced multiple organ failure in comparison with a control group of similar age it was abundantly clear that this was not due to either a global reduction in mitochondrial gene transcripts or to impaired in vivo total mitochondrial protein synthesis.

DOX disrupted cardiac mitochondrial biogenesis, as demonstrated by decreased mtDNA levels and altered transcript levels for multiple mitochondrial genes encoded by both nuclear and mitochondrial genomes.

The supernatant containing cytoplasmic and mitochondrial enzymes was subjected to enzyme activity analysis.

This dye becomes fluorescent upon reduction by mitochondrial enzymes in metabolically active cells.

Mitochondrial enzymes play central roles in anabolic growth, and acetylation may provide a key layer of regulation over mitochondrial metabolic pathways.

To improve the mitochondrial respiratory capacity, GBE may act on one or several mitochondrial enzymes.

Defects of three mitochondrial enzymes are reported.

A canonical example of this class are the mitochondrial enzymes.