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The RegPredict tool allows simultaneous analysis of multiple microbial genomes and integrates information on location of regulatory sites, gene orthologs, operon predictions, and functional gene annotations.
RegPredict allows for the simultaneous analysis of multiple microbial genomes and integrates information on gene orthologs, operon predictions, and functional gene annotations.
Motivation: The Prokaryotic-genome analysis Tool (PGAT) is a web-based database application for comparing gene content and sequence across multiple microbial genomes facilitating the discovery of genetic differences that may explain observed phenotypes.
In the Yersinia module, using a combination of BLAST, ASAP, and Mauve enables students to analyze genotypic differences across multiple microbial genomes and derive bioinformatics-driven hypotheses that may address known epidemiological, historical, experimental, and phenotypic information.
However, as it is now possible to sequence multiple microbial genomes in a single day at low cost using a single sequencing machine [ 3], it is no longer feasible to manually curate the annotation of all sequenced genomes.
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Detoxification genes are frequently present in multiple copies in microbial genomes, where gene multiplications are selected to yield high expression and/or functionally distinct paralogs to optimize survival and growth under harsh conditions.
But the latter involves multiple (often 10) reference microbial genomes.
The clustering of these frequency patterns is much simpler than performing multiple sequence alignment of whole microbial genomes.
First, microbial genomes often harbor multiple CRISPR arrays.
Furthermore, our comprehensive comparative analysis of genomic characteristics of 895 microbial genomes reveals that KN400 is a characteristic microbial genome and is not an outlier in the space of all microbial genomes.
The use of multiple guide trees is a particularly important feature in microbial genomes, which are subject to lateral gene transfer.
More suggestions(15)
multiple microbial species
multiple microbial targets
multiple microbial pathogens
multiple other genomes
multiple microbial sources
multiple microbial agents
multiple microbial exposures
multiple microbial factors
multiple microbial samples
multiple microbial determinants
multiple microbial contaminants
multiple microbial biomarkers
multiple mammalian genomes
multiple microbial flora
multiple microbial products
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