Sentence examples for multiple methylation markers from inspiring English sources

In summary, multiplex qMSP is a high-throughput, quantitative assay to analyze multiple methylation markers in a single reaction.

However, determining the methylation status of multiple methylation markers separately is time consuming and relatively large amounts of sample material are needed.

Major advantages of multiplexing are less hands-on time and less amounts of DNA required to determine the methylation status of multiple methylation markers as compared to running multiple singleplex analyses.

As has been described in sporadic AD cases [4], neurons of the AD twin exhibited dramatic decrements across multiple DNA methylation markers compared to the non-AD twin.

SAM then serves as a source of methyl groups for multiple methylation reactions, including the methylation of DNA.

Our resource of a large colorectal cancer sample obtained from two large prospective cohorts (representing a relatively unbiased sample compared to a single-hospital-based sample) has provided a sufficient power to evaluate the 16 methylation markers, and to simultaneously assess independent relations of CIMP-high with multiple clinical and tumoral molecular variables.

Hypermethylation of all these methylation markers was significantly increased in MS patients compared to healthy controls.

DNA methylation markers could serve as useful biomarkers, both as markers for progression and for urine-based diagnostic assays.

We found that DNA methylation markers outperformed mRNA, sjTREC, and telomere length in age predictive power.

Accumulating evidence suggests that DNA methylation markers could serve as sensitive and specific cancer biomarkers.

With the emergence of high-throughput technologies, ranging from microarrays to next-gen sequencing, genome-wide scanning to search for disease-related DNA methylation markers is now possible.