The system is designed to simultaneously support multiple heterogeneous intelligent methodologies, such as neural networks, expert systems, fuzzy logic, neural networks and genetic algorithms.
In addition, statistical methodologies such as multiple testing and population stratification adjustments, which to date have been almost completely absent in these studies, need to be routinely employed as well.
However, new amplification methodologies such as multiple annealing and looping-based amplification cycles, which enable over 90%% genome coverage and can accurately detect mutations and copy number variations [ 59], are in development and have the potential to greatly improve single-cell sequencing.
Other methodologies such as forced RFLP and sequencing of multiple cloned products could be applied to determine if these mutations are homozygous or heterozygous.
The biomarker candidates need to be validated in a greater and statistically significant universe of individual samples using distinct methodologies such as Western blot, ELISA or single and multiple reaction monitoring (SRM or MRM).
The field's interdisciplinary research combines multiple methodologies, including mathematical analysis, computer modeling, software system design, experimental studies, and critical social evaluations, from such traditional disciplines as computer science, cognitive psychology, social science, cultural studies, and history.
Integrated, holistic methodologies such as an eco-system health approach (32) are necessary to understand the multiple dimensions of the environmental, health and socioeconomic issues that require sustainable solutions.
The field's interdisciplinary research combines multiple methodologies, including mathematical analysis, computer modeling, hardware and software system design, experimental studies, and critical social evaluations, from such traditional disciplines as computer science, cognitive psychology, social science, cultural studies, and history.
Denying a role for genes in why people turn out differently is to deny decades of converging scientific evidence from multiple methodologies.
Research designs combining multiple methodologies were the norm.
