Sentence examples for multiple metabolic toxicities from inspiring English sources
The multiple metabolic toxicities of the A-FLIGHT acronym result in an abundance of ROS.
This quartet is also associated with multiple metabolic toxicities resulting in the production of reactive oxygen species.
Metabolic syndrome, prediabetes, type 2 diabetes mellitus, and their parallel companion (atheroscleropathy) are associated with multiple metabolic toxicities and chronic injurious stimuli.
The metS is associated with multiple metabolic toxicities referred to as the A-FLIGHT-U toxicities, which result in the production of ROS (table 3).
MS, PD, and T2DM are associated with multiple metabolic toxicities, which are responsible for reactive oxygen species (ROS) production (table 3).
Undoubtedly the essential cofactor tetrahydrobiopterin (BH4) becomes depleted during this chronic ischemia in the subcutaneous tissue from the multiple metabolic toxicities.
In addition to correcting the underlying multiple metabolic A-FLIGHT toxicities and positive regulators of VOC (table 3, 5), a strong consideration to newer therapies should be entertained in order to prevent, slow, and alter the morbid – mortal natural history of the dreaded complications associated with CPLX – CUA.
There are undoubtedly multiple causes for this decrease in perlecan and the multiple metabolic A-FLIGHT-U toxicities are related to this decrease in perlecan within the BM (table 1, 4).
As glutamine is the most abundant amino acid in the body and is used in multiple metabolic reactions, targeting glutamine without toxicity might be more difficult than targeting glucose (220, 221).
Dietary energy reduction will simultaneously target multiple metabolic signaling pathways without causing adverse effects or toxicity (208).
Additional factors likely to be significant contributors to MTXPG variability include pharmacokinetic variation, physiological and developmental differences in oral absorption, transporter expression and the individual genotypes for MTX multiple metabolic pathways that have been associated with both efficacy and toxicity of MTX [ 48– 50].
