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Thus, homeostasis of cytokinin activity is maintained by multiple metabolic systems.
Emerging evidence points to the parallel targeting of multiple metabolic systems as a possible solution to bringing about efficacious and sustained weight loss and metabolic improvements.
The same situation applies to retinoid X receptors (RXR), because RXRs are well-known obligate heterodimer partners for PPAR actions in controlling the storage and use of energy, and they play integrative roles across multiple metabolic systems [ 23].
Similar(57)
This was due to multiple affected metabolic systems each containing numerous similarly-behaving components.
However, the cerebral capillaries are the site of the blood brain barrier (BBB) and consequently these three routes are restricted by the presence of tight junctions between the endothelial cells, the lack of intracellular fenestrations in brain endothelial cells, the paucity of endocytotic vesicles as well as by the presence of multiple metabolic enzymes and diverse transport systems (Fig. 1).
In particular, schemes that control precise patterns of gene expression as a function of time are essential for balancing multiple metabolic objectives in natural and synthetic systems.
The assessment of insulin action is complex because insulin has multiple metabolic functions that differ across organ systems and require different doses of insulin to achieve maximal effects (5).
We propose an algorithm to reconstruct the evolutionary history of DPR networks across multiple species and categorize the mechanisms of metabolic systems evolution in terms of network changes.
As with most complex metabolic systems, numerous GP with multiple functions need to be considered to fully evaluate the pharmacogenetics of cancer chemoprevention.
These associations in human studies, in conjunction with functional studies in model systems, have implicated adiponectin in multiple metabolic processes.
Proteins involved in several multiple metabolic pathways, including glycolysis, pentose phosphate pathway, anti-oxidative systems, photosynthesis and cell wall synthesis, were downregulated, especially during the climacteric burst in respiration and during the senescent stages of fruit development.
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