Third, mice were exposed for 15 weeks to a high-fat diet before and after which multiple peripheral metabolic measures were assessed.
The methodology provides information on >100 primary metabolic measures and multiple derived variables with clear biochemical interpretation and significance (21).
The multiple linear regression models that used metabolic measures as the dependent variables included the following independent variables: age, SES, total body fat mass, fat-free soft tissue mass, waist circumference, sitting time, total MVPA, work MVPA, leisure MVPA and walking for travel MVPA.
Furthermore, LOX inhibition improves multiple metabolic parameters: normalizing glucose, insulin and triglyceride levels and reducing the homeostatic model assessment (HOMA) index – a measure of insulin resistance.
Mitochondrial dysfunction is a hallmark of multiple metabolic complications.
Zhang, W. et al. FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression.
As shown here, we were able to identify multiple metabolic enzymes and upstream regulators as targets of miR-155.
The circadian clock is an endogenous, time-tracking system that directs multiple metabolic and physiological functions required for homeostasis.
Since the pathogenesis of metabolic syndrome has multiple metabolic origins, there is no single treatment for it.
Type 2 diabetes mellitus (NIDDM) is a complex disorder encompassing multiple metabolic defects.
Type 2 diabetes mellitus is a complex disorder encompassing multiple metabolic defects.
