Sentence examples for multiple metabolic defects from inspiring English sources

PGC-1α knockout mice exhibit multiple metabolic defects, such as obesity, neurodegeneration and cardiomyopathy [9], [10].

Thus, aromatase knock-out mice reveal multiple metabolic defects (Jones et al. 2001), and aromatase deficiency due to germline mutations causes osteopenia as well as metabolic disturbances in both genders (Morishima et al. 1995, Rochira & Carani 2009).

These analyses suggest that acetylation reaches a sufficient stoichiometry in SIRT KO animals to account for the metabolic defects seen in these animals, particularly if multiple proteins and acetylation sites are affected in a common metabolic pathway.

All regulate glucose, but they do so by targeting different metabolic defects.

Other metabolic defects may make their appearance only relatively late in life.

Studies on mice have clearly shown that allowing them to eat only when they are naturally awake, which is at night because they are nocturnal, results in fewer metabolic defects.

In the 1940s Butenandt's researches on eye-colour defects in insects proved that specific genes control the synthesis of enzymes needed in various metabolic processes, and that mutations in those genes can result in metabolic defects.

The consequences range from stress to metabolic defects, neurodegenerative diseases or even neoplastic transformations [159].

Mitochondrial dysfunction is a hallmark of multiple metabolic complications.

Since the pathogenesis of metabolic syndrome has multiple metabolic origins, there is no single treatment for it.

Several metabolic defects, such as phenylketonuria, are associated with autistic symptoms.