AMPK acts as a cellular integration node for various nutrient and hormone signals, and subsequent changes in AMPK activity regulates multiple metabolic pathways of glucose metabolism [ 7].
In contrast to hydroxyurea, which appeared to have a highly specific effect on p53 signaling, serum starvation induced changes in multiple pathways, perturbing metabolic activity and also dramatically changing the abundances of chromatin regulators and core nucleosome components.
Of the glycosylated proteins, most were related to metabolic activities and carry multiple N-linked glycosylation sites.
Thus, homeostasis of cytokinin activity is maintained by multiple metabolic systems.
PDI and PDI-like proteins are responsible for multiple metabolic functions, including secretory protein folding, chaperone activity and redox signalling.
Functional analyses across the asterids, rosids, and monocots recently confirmed that, post polyploidization, genes involved in "biological regulation" were retained in multiple copies (or were resistant to fractionation) while those responsible for metabolic activities tended to lose copies [ 66].
Pharmacological activation of NAD+ thus stimulates the activity of multiple sirtuin in a compartment-specific manner to exert its beneficial effects on multiple metabolic pathways which is in contrast to STAC's that specifically stimulate the activity of SIRT1 pathway.
Recently, metabolic activities have reemerged as a process able to generate other multiple cellular responses.
A two-way ANOVA with Tukey's multiple comparisons post-test was also used to compare changes in loss in metabolic activities of cells treated with different polymers using side chain and base monomer as the parameters.
Mitochondrial dysfunction is a hallmark of multiple metabolic complications.
