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Recently, a systematic review showed that physical function, illness severity, cognition, comorbidity, presenting medical diagnosis, multiple medication use, and age could affect hospital length of stay (LOS), readmissions, discharge destination and mortality [ 16].
Thus, it became necessary to evaluate and clarify terminology currently used in the medical literature to describe multiple medication use in the older adult before evaluating the prevalence of polypharmacy.
Previous studies have suggested that multiple comorbidities and multiple medication use has been associated with decreased mobility and gait instability, both linked to falls (Stevens and Rudd 2014; Rubenstein 2006; Tinetti et al. 2014; Hausdorff et al. 1997; Leipzig et al. 1999).
Multiple medication use or polypharmacy was defined as the use of ≥5 regular prescription medicines.
The plethora of pharmaceutical options must be balanced with the potential risk of multiple medication use.
The authors recommend use of less ambiguous terminology such as hyperpharmacotherapy or multiple medication use.
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OBJECTIVE: To assess the quality of medication prescribing in ambulatory elderly patients on multiple medications using the Medication Appropriateness Index (MAI).
One group of authors suggested that passive hepatic congestion, accumulation of metabolites, and/or interactions with multiple medications used in the ICU may justify lower dose requirements [ 17].
Preskorn (2005) recommends the alternative phrase 'multiple medication use.' However, Preskorn's phrase has a neutral connotation because concomitant use of multiple drugs is often supported by evidence-based guidelines for various disease states (Preskorn 2005).
In spite of the guidelines and recommendations that exist for the management of OA, inappropriate multiple analgesic medication use among OA patients may represent an additional burden on a health-care system that is struggling to adapt to an increasing prevalence of chronic diseases [ 7].
Medicines management is consequently complex, with multiple medications in use.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com