Sentence examples for multiple mediators in from inspiring English sources

Presence of multiple mediators in the TME and lack of interferon γ (IFNγ) allow activation of TAMs.

Moreover, the high serum levels of a broad range of cytokines detected in these patients [ 34] suggest the involvement of multiple mediators in specific organ injury [ 8, 9, 39].

However, the activation ratio and peak intensity remained considerable after blocking IP3R with 2-APB, suggesting that IP3 bound with IP3R might be only one of multiple mediators involved in intracellular calcium release Open image in new window Figure 5 Effects of blocking IP3 and membrane calcium channel on the calcium signaling of neutrophils on P-selectin in flow.

The model was explored using Conditional Process analysis, http://www.afhayes.com/, [60, 61], which allows for assessment of multiple mediators working in parallel using recommended bootstrap methodology [62].

Indeed, synovial fibroblasts make up the shroud-like pannus characteristic of the rheumatoid joint and are an important source of multiple mediators implicated in arthritis.

Multiple mediators are involved in this inflammatory response [ 7], but past attempts to modulate it by targeting single components have failed, at least at the clinical phase [ 8].

We have shown that extending the mediation framework to multiple mediators gives rise to complexities (in terms of multiplicity of definitions) and challenges (for identification) beyond what might have been anticipated.

Multiple mediators have been implicated in the process of angiogenesis [ 5, 6].

Note that such a sequential treatment of multiple mediators is also discussed in VanderWeele and Vansteelandt (2014).

The performance of NLMMs and SEMs in other scenarios, such as the analysis of nominal and ordinal outcomes as well as the case of multiple mediators, should be evaluated in future studies.

Multiple mediator models in which MHSE is pitted along-side other theoretically relevant mediator variables should be studied.