Sentence examples for multiple mediators and from inspiring English sources

For example, in scenarios with multiple mediators and pathways, the advantages and disadvantages of NLMMs relative to SEMs may differ.

It can be used to predict the effects of altered pathway components, collective actions of multiple mediators and the potential impact to various diseases.

We therefore adopt the fully parametric approach, implemented by Monte Carlo simulation, extending it to handle multiple mediators and incorporating the sensitivity analysis of Section Identification and sensitivity analysis under a particular parametric model.

Since the detailed mechanisms underlying this activation are still unclear, simultaneous investigation of multi-stimuli activation of SFBs offers the possibility to elucidate the regulatory effects of multiple mediators and to gain new insights into disease pathogenesis.

There was no evidence of a serial pathway between neurocognition and multiple mediators and violence, and only social cognition and violence proneness operated in parallel as significant mediators accounting for 46%% of the variance in violent incidents.

However, RAS does not represent a linear cascade, but is composed of a sophisticated interplay between multiple mediators, receptors, and enzymes.

We ran two mediation analyses: (1) single mediation models (unadjusted, a model that has single mediator), (2) multiple mediation model (adjusted, to obtain the significance of individual mediators within the context of a model that has multiple mediators simultaneously and account for the biological direction between mediators).

The innate immune system is 'primed' by activation of PRRs by PAMPs or DAMPs, which leads to activation of numerous proinflammatory transcription factors, the best characterized being nuclear factor kappa-B (NF-κB) and activator protein-1 (AP-1), with subsequent transcription of multiple mediators (including cytokines and chemokines) and receptors.

This is achieved by multiple mediators that initiate and modulate the extent and duration of and also resolve inflammatory processes.

To enable more comprehensive analysis of signalling in endothelial permeability, there is a need to develop an expanded ODE model that covers the signalling mediated by multiple mediators, particularly thrombin, histamine and VEGF.

Multiple mediators of inflammation and injury (ICAM-1, NF-κB, RAGE, PCIII, and E-cadherin) were measured in lung tissue at necropsy, but none were significantly different either within or between groups.