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Multiple mechanisms were explored such as genetic alterations, activation of bypass signaling, and phenotypic transition.
Although multiple mechanisms were postulated for these beneficial effects at cellular level, early transcriptional changes were unknown.
In the literature, multiple mechanisms were proposed to explain this phenomenon, one of which stated that the white etching matter formed around a subsurface crack is a symptom of crack faces rubbing which leads to local changes in the material microstructure.
Importantly, to our knowledge, all these algorithms testing multiple mechanisms were exclusively validated using human curated and manually annotated gene sets (e.g. Gene Ontology).
Because all of these rely on the physical and chemical properties of molecules themselves, one can reasonably anticipate that multiple mechanisms were operative and may have operated synergistically in protocell assembly.
Similar(55)
Multiple mechanisms are probably involved.
These findings suggest that multiple mechanisms are responsible for these headaches.
Our data indicate that multiple mechanisms are likely to be involved in development of idiosyncratic DILI in man caused by numerous drugs, e.g. the anticonvulsant chlorpromazine.
When confronted with stressors, the top-down modulation from the PFC to the central nucleus of the amygdala is disinhibited, resulting in multiple mechanisms being activated or inhibited (level II) leading to an increase in HR (level III).
Antimicrobial resistance develops rapidly under selection pressure, and multiple mechanisms are responsible: (hyper- production of enzymes, suchyper- productionses and DNA-gyrases, active efflux pumps, and permeability changes [21].
"It has been suggested that multiple mechanisms are involved," Gu said.
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